I get asked often what wines go well with Thanksgiving Dinner. The anwer is 'none'. There really isn't any wine that pairs with the traditional rich and sweet Thanksgiving dinner. At least not in the classic way of pairing.
The holiday is also one where you're likely to have a lot of guests in the house who don't drink wine often. The complexities of an aged Burgundy are likely wasted, and Aunt Mildred isn't going to be impressed that you opened that $200 bottle.
So keep it simple is what I recommend, and open some crowd pleasers. Pull out wines with bold fruit and easy textures. Oaked Chardonnay's are a favorite of many, and if you can't bring yourself to buy a bottle, try opening a Viognier. The white wine drinkers will love the floral nose and sweet fruit. Avoid Sauvignon Blanc, it's spiky acidity is off putting to many who don't drink wine often.
For reds I always open a Zinfandel. For one it's the most American of wines. It also is full bodied and fruity, another crowd pleaser. Syrah or a Shiraz from Australia will have many of the same qualities. While many new style Pinot Noirs from California would fit, you should know what you are opening before hand. A bold wine from Sea Smoke would make everyone happy, but a Chambolle-Musigny like wine from Windy Oaks would puzzle many of your guests.
When the pies come out, bring out some sweet treat dessert wines or better still a nice Brandy.